JASPAR - REST - BP000587.1 - profile summary

This page shows detailed deep learning-derived predictions and motifs for REST in MCF-7 using a single trained BPNet model. Please scroll down the page to browse other models for this transcription factor.

Model details

Name:	REST
Model ID:	BP000587.1
Cell line/tissue:	MCF-7
Class:	C2H2 zinc finger factors
Family:	Factors with multiple dispersed zinc fingers
JASPAR ID:	MA0138.3
Taxon:	Vertebrates
Species:	Homo sapiens
Data Type:	ChIP-seq
Uniprot ID:	Q13127
Source:	ENCSR000BSP
Model:	BPNet
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Sequence logo

Motif name: counts.pos_patterns.pattern_1

Number of seqlets: 2611

Contribution weight matrix (CWM)

A [	0.00	-0.01	0.01	-0.00	-0.00	0.00	0.00	-0.00	0.00	-0.00	0.04	-0.00	-0.00	0.00	0.00	0.00	0.00	0.00	-0.00	0.07	0.02	0.00	-0.00	]
C [	-0.00	0.00	0.04	-0.00	0.20	-0.00	0.00	-0.00	0.25	0.21	-0.00	-0.00	0.00	0.00	0.00	0.00	0.21	0.00	-0.00	0.00	0.00	0.01	0.00	]
G [	0.05	0.04	-0.00	0.06	-0.00	0.00	0.12	-0.00	0.00	0.00	0.01	-0.00	0.15	0.25	0.00	0.05	0.00	0.00	0.12	0.00	-0.00	0.00	0.00	]
T [	-0.00	0.00	-0.00	-0.01	-0.00	0.18	-0.00	0.12	-0.00	-0.00	-0.01	0.03	-0.00	0.00	0.24	-0.01	-0.00	0.14	-0.00	-0.00	-0.00	-0.00	0.00	]

Frequency matrix

A [	644	598	562	553	719	600	607	643	570	551	474	499	490	577	705	462	284	724	503	20	26	162	117	3	14	1329	690	147	6	13	336	15	26	190	1711	1260	672	671	646	683	615	720	607	561	575	536	524	565	637	688	]
C [	714	754	735	649	658	714	636	672	659	645	710	724	923	740	346	128	515	1192	360	2431	16	381	68	2514	2507	249	197	26	3	12	619	2550	81	62	288	584	707	716	669	654	762	674	700	773	710	730	698	671	703	689	]
G [	699	671	660	720	654	718	784	826	670	899	682	811	605	615	895	1659	1415	96	1310	25	14	2032	258	15	6	464	337	2367	2591	7	1459	18	19	2229	488	369	690	574	583	669	645	600	691	594	692	718	686	746	619	604	]
T [	554	588	654	689	580	579	584	470	712	516	745	577	593	679	665	362	397	599	438	135	2555	36	2168	79	84	569	1387	71	11	2579	197	28	2485	130	124	398	542	650	713	605	589	617	613	683	634	627	703	629	652	630	]

Hypothetical CWM

A [	0.00	-0.00	0.00	0.00	0.02	-0.05	0.04	0.00	-0.09	-0.07	0.05	-0.02	-0.06	-0.08	0.09	0.02	0.02	-0.06	-0.08	0.04	-0.08	-0.14	-0.01	0.10	0.05	0.01	-0.01	0.01	]
C [	0.01	0.02	0.02	0.01	-0.04	0.04	0.11	0.01	0.21	-0.05	0.04	-0.06	0.26	0.22	-0.02	0.02	-0.04	-0.04	-0.04	0.06	0.21	0.03	-0.04	0.01	0.03	0.03	0.02	0.02	]
G [	0.02	0.02	0.02	0.05	0.08	0.08	-0.09	0.13	-0.06	-0.00	0.16	0.02	-0.10	-0.01	0.08	0.02	0.17	0.25	-0.07	0.10	-0.01	0.02	0.14	0.03	-0.03	0.02	0.02	0.03	]
T [	-0.01	-0.00	-0.00	0.01	-0.01	0.02	0.01	-0.04	0.02	0.18	-0.12	0.14	-0.00	-0.01	-0.03	0.07	-0.04	-0.05	0.24	-0.07	-0.03	0.14	-0.02	-0.07	0.01	0.00	0.01	-0.01	]

Other motifs identified by TF-MoDISco

Motif name: counts.pos_patterns.pattern_0

Num. of seqlets: 3305

CWM

PFM

HCWM

Motif name: counts.pos_patterns.pattern_2

Num. of seqlets: 1331

CWM

PFM

HCWM

Motif name: counts.pos_patterns.pattern_4

Num. of seqlets: 590

CWM

PFM

HCWM

Motif name: counts.pos_patterns.pattern_5

Num. of seqlets: 226

CWM

PFM

HCWM

Motif name: counts.pos_patterns.pattern_6

Num. of seqlets: 197

CWM

PFM

HCWM

Motif name: counts.pos_patterns.pattern_7

Num. of seqlets: 134

CWM

PFM

HCWM

Motif name: counts.pos_patterns.pattern_10

Num. of seqlets: 44

CWM

PFM

HCWM

Motif name: counts.pos_patterns.pattern_12

Num. of seqlets: 26

CWM

PFM

HCWM

Motif name: counts.neg_patterns.pattern_4

Num. of seqlets: 24

CWM

PFM

HCWM

Motif name: counts.neg_patterns.pattern_5

Num. of seqlets: 22

CWM

PFM

HCWM

27 profiles found for the same TF (REST) in other cell types/tissues

Model ID	Name	Data Source	Cell line/tissue	Species	JASPAR ID
BP000593.1	REST	ENCSR137ZMQ	K562	Homo sapiens	MA0138.3
BP000594.1	REST	ENCSR663WAR	H1	Homo sapiens	MA0138.3
BP000595.1	REST	ENCSR867WPH	liver	Homo sapiens	MA0138.3
BP000596.1	REST	ENCSR871KYB	GM23338	Homo sapiens	MA0138.3
BP000597.1	REST	ENCSR892DRK	A549	Homo sapiens	MA0138.3
BP000598.1	REST	ENCSR893QWP	liver	Homo sapiens	MA0138.3
BP000599.1	REST	ENCSR896UBV	HEK293	Homo sapiens	MA0138.3