Detailed information of deep learning profile BP000587.1

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This page shows detailed deep learning-derived predictions and motifs for REST in MCF-7 using a single trained BPNet model. Please scroll down the page to browse other models for this transcription factor.

Model details

Name: REST
Model ID: BP000587.1
Cell line/tissue: MCF-7
Class: C2H2 zinc finger factors
Family: Factors with multiple dispersed zinc fingers
JASPAR ID: MA0138.3
Taxon: Vertebrates
Species: Homo sapiens
Data Type: ChIP-seq
Uniprot ID: Q13127  
Source: ENCSR000BSP
Model: BPNet
Download trained model
Download TF-MoDISco Report

Sequence logo

 

Contribution weight matrix (CWM)

 
A [ 0.00 -0.01 0.01 -0.00 -0.00 0.00 0.00 -0.00 0.00 -0.00 0.04 -0.00 -0.00 0.00 0.00 0.00 0.00 0.00 -0.00 0.07 0.02 0.00 -0.00 ]
C [ -0.00 0.00 0.04 -0.00 0.20 -0.00 0.00 -0.00 0.25 0.21 -0.00 -0.00 0.00 0.00 0.00 0.00 0.21 0.00 -0.00 0.00 0.00 0.01 0.00 ]
G [ 0.05 0.04 -0.00 0.06 -0.00 0.00 0.12 -0.00 0.00 0.00 0.01 -0.00 0.15 0.25 0.00 0.05 0.00 0.00 0.12 0.00 -0.00 0.00 0.00 ]
T [ -0.00 0.00 -0.00 -0.01 -0.00 0.18 -0.00 0.12 -0.00 -0.00 -0.01 0.03 -0.00 0.00 0.24 -0.01 -0.00 0.14 -0.00 -0.00 -0.00 -0.00 0.00 ]

Frequency matrix

       
A [ 644 598 562 553 719 600 607 643 570 551 474 499 490 577 705 462 284 724 503 20 26 162 117 3 14 1329 690 147 6 13 336 15 26 190 1711 1260 672 671 646 683 615 720 607 561 575 536 524 565 637 688 ]
C [ 714 754 735 649 658 714 636 672 659 645 710 724 923 740 346 128 515 1192 360 2431 16 381 68 2514 2507 249 197 26 3 12 619 2550 81 62 288 584 707 716 669 654 762 674 700 773 710 730 698 671 703 689 ]
G [ 699 671 660 720 654 718 784 826 670 899 682 811 605 615 895 1659 1415 96 1310 25 14 2032 258 15 6 464 337 2367 2591 7 1459 18 19 2229 488 369 690 574 583 669 645 600 691 594 692 718 686 746 619 604 ]
T [ 554 588 654 689 580 579 584 470 712 516 745 577 593 679 665 362 397 599 438 135 2555 36 2168 79 84 569 1387 71 11 2579 197 28 2485 130 124 398 542 650 713 605 589 617 613 683 634 627 703 629 652 630 ]

Hypothetical CWM

   
A [ 0.00 -0.00 0.00 0.00 0.02 -0.05 0.04 0.00 -0.09 -0.07 0.05 -0.02 -0.06 -0.08 0.09 0.02 0.02 -0.06 -0.08 0.04 -0.08 -0.14 -0.01 0.10 0.05 0.01 -0.01 0.01 ]
C [ 0.01 0.02 0.02 0.01 -0.04 0.04 0.11 0.01 0.21 -0.05 0.04 -0.06 0.26 0.22 -0.02 0.02 -0.04 -0.04 -0.04 0.06 0.21 0.03 -0.04 0.01 0.03 0.03 0.02 0.02 ]
G [ 0.02 0.02 0.02 0.05 0.08 0.08 -0.09 0.13 -0.06 -0.00 0.16 0.02 -0.10 -0.01 0.08 0.02 0.17 0.25 -0.07 0.10 -0.01 0.02 0.14 0.03 -0.03 0.02 0.02 0.03 ]
T [ -0.01 -0.00 -0.00 0.01 -0.01 0.02 0.01 -0.04 0.02 0.18 -0.12 0.14 -0.00 -0.01 -0.03 0.07 -0.04 -0.05 0.24 -0.07 -0.03 0.14 -0.02 -0.07 0.01 0.00 0.01 -0.01 ]

Other motifs identified by TF-MoDISco

 

Motif name: counts.pos_patterns.pattern_0

Num. of seqlets: 3305

CWM

PFM

     

HCWM

Motif name: counts.pos_patterns.pattern_2

Num. of seqlets: 1331

CWM

PFM

     

HCWM

Motif name: counts.pos_patterns.pattern_4

Num. of seqlets: 590

CWM

PFM

     

HCWM

Motif name: counts.pos_patterns.pattern_5

Num. of seqlets: 226

CWM

PFM

     

HCWM

Motif name: counts.pos_patterns.pattern_6

Num. of seqlets: 197

CWM

PFM

     

HCWM

Motif name: counts.pos_patterns.pattern_7

Num. of seqlets: 134

CWM

PFM

     

HCWM

Motif name: counts.pos_patterns.pattern_10

Num. of seqlets: 44

CWM

PFM

     

HCWM

Motif name: counts.pos_patterns.pattern_12

Num. of seqlets: 26

CWM

PFM

     

HCWM

Motif name: counts.neg_patterns.pattern_4

Num. of seqlets: 24

CWM

PFM

     

HCWM

Motif name: counts.neg_patterns.pattern_5

Num. of seqlets: 22

CWM

PFM

     

HCWM

27 profiles found for the same TF (REST) in other cell types/tissues

Display profiles


Model ID Name Data Source Cell line/tissue Species JASPAR ID Sequence logo
BP000572.1 REST ENCSR000ATM K562 Homo sapiens MA0138.3
BP000573.1 REST ENCSR000BGF GM12878 Homo sapiens MA0138.3
BP000574.1 REST ENCSR000BHM H1 Homo sapiens MA0138.3
BP000575.1 REST ENCSR000BJJ SK-N-SH Homo sapiens MA0138.3
BP000576.1 REST ENCSR000BJL HepG2 Homo sapiens MA0138.3
BP000577.1 REST ENCSR000BJO Panc1 Homo sapiens MA0138.3
BP000578.1 REST ENCSR000BJP PFSK-1 Homo sapiens MA0138.3
BP000579.1 REST ENCSR000BMN HeLa-S3 Homo sapiens MA0138.3
BP000580.1 REST ENCSR000BMW K562 Homo sapiens MA0138.3
BP000581.1 REST ENCSR000BOT HepG2 Homo sapiens MA0138.3
Showing 10 profiles of page 1 from 3 pages